Piglet nutrition, no resistance, new biotechnology, do you make it? Teach trough material summit forum to give you the answer

The sun is shining brightly in Yangcheng, and we talk about the future with the light. August 20, creep feed the Ninth National Development Forum, set up 10 field experts report forums, wonderful continues ......

meeting site

am Moderator: Professor Wang Junjun Animal Science and Technology, vice president of China Agricultural University

pm Moderator: Professor Li Yanhua, School of Veterinary Medicine, Northeast Agricultural University, Vice Chairman of Zhongguancun Traditional Chinese Veterinary Medicine Industry Technology Innovation Strategic Alliance

Expert report

Speaker: Zhu Wensen Dr. Beijing Enruikang Agricultural Technology Consulting Co., Ltd.

Strategies for improving the health of piglets and improving growth performance under non-resistant diet conditions" Dr. Zhu first analyzed the causes and effects of the decline in the antibiotic era, and introduced feasible measures to replace the use of antibiotics, such as improving genetic basis, optimizing diets, and detailed management , All in, all out, better animal environment, etc.

He emphasized that we must pay attention to biological safety and demonstrated how swine fever enters the pig farm. It is the diseased pigs that enter the pig farm through transportation, so it is worth paying attention to cleaning the transportation vehicles. Dr. Zhu uses a "three-stage segmentation system" for the contact of pigs with the external environment, and transitions the "dirty area" from the "clean area". The pig farm needs to have a transfer station or use a "six-stage segmentation system" to optimize pigs. The field is isolated from the external environment.

then analyzes the immune system and divides the immune system into adaptive immunity and innate immunity. The first barrier of the body's defense is to hinder or prevent pathogenic microorganisms from entering the body, and the second barrier is to deal with some that have managed to pass the first barrier. A barrier to pathogens entering the body tissues. The difference in immunity is affected by factors such as season, environment, stress and malnutrition. Pay attention to the temperature, humidity, ventilation, and ventilation of the pig farm. The purpose of ventilation is to control the temperature in summer and control the humidity in cold days. Effective ventilation can increase the capacity of the barn. By reducing the density, the barn with poor ventilation (relying solely on window ventilation) can be improved Works well. The control strategy of intestinal diseases should reduce stress.

Speaker: Dr. Guo Pengfei, Director of Cargill Animal Nutrition Pig Technology Application

Report topic: "Key points of suckling pig nutrition in the era of resistance-free piglets and strategies for teaching troughs"

Dr. Guo said that the current market for non-resistant products is still quite different Yes, the suckling piglet on the farm is currently facing challenges.

feed without resistance will undoubtedly have an impact on animal performance. Cargill proposes "5H" anti-animal health solutions. "5H" refers to feed health, nutrition health, intestinal health, immune health, and farm health. Raw material health includes the optimization and matching of raw materials, selection of high-digestibility raw materials (pretreatment of raw materials, control of fermentable protein) essential fatty acids, selection of biosafety and controllable raw materials, and reduction of mycotoxin pollution risks; nutrition technology includes cleaning The use of energy system, the establishment of digestible amino acid model (amino acid system is not static), low-protein technology, intestinal fermentable protein, fermentable carbohydrate, fatty acid nutrition and other aspects are reasonable control. The selection of functional additive products should pay attention to its role in inhibiting pathogenic bacteria, promoting beneficial bacteria, stimulating digestion and absorption, enhancing intestinal health and immunity, and reducing oxidative stress. In farm management, attention should be paid to biological safety, environmental improvement, and feeding management. , Feeding methods and other details. Systematic nutrition solutions and farm solutions can help customers achieve animal health and maintain good production performance under non-resistant feed conditions.

Speaker: Dr. Yong Peng, Director of Nutrition Technology, Shanghai Meinong Biotechnology Co., Ltd.

Report topic: "Nutrition technology strategy for suckling piglet intestinal health under the background of anti-antibiotics"

From the perspective of antibiotic efficacy, antibiotics mainly act on the intestine , The intestine is an important digestion and absorption organ,80% of digestion and absorption are completed in the intestine; the intestine is also an important defense organ, not only has a barrier function, but also the body's largest immune organ. Therefore, the essence of replacement antibiotics is to replace the efficacy of feed antibiotics, and the key to replacement antibiotics is to maintain pig’s intestinal health. Dr.

Peng pointed out that the health of the intestinal tract after banning anti-antibiotics is facing challenges such as the easy destruction of the intestinal cell structure and the breaking of the intestinal microbial balance. Based on these two points, he gave the "12345" intestinal health strategy, which is a major goal of : intestinal health, adapting to the intestine, protecting the intestine, making up for the intestine, and repairing the intestine; the two cores of : Protect intestinal structure from damage, adjust intestinal balance disorders; three directions of : good digestion and absorption of nutrients in , ensure the balance of intestinal flora, and ensure normal immune function; four elements of : nutrients and levels, Nutrition source, nutritional structure, functional additives; five major paths: increase feed intake, improve digestion and absorption of nutrients, reduce intestinal injury, strengthen repair after intestinal injury, and regulate flora imbalance. The two core elements of non-resistant feed formulation: good protein nutrition and good use of functional additives. Functional additives ensure pig intestinal health from three aspects: feeding, digestion and absorption. Dr. Peng recommends the combined use of plant extracts, butyric acid/glutamine, prebiotics/prebiotics and other products. At the same time, products such as "Youyue Series", "Yimei Sweet Series", "Yimei Protein", "Fumex Acid" and "Weimei Acid Plus" were also displayed.

Speaker: Professor Li Yanhua, Northeast Agricultural University School of Animal Medicine, Vice Chairman of Zhongguancun Traditional Chinese Veterinary Medicine Industry Technology Innovation Strategic Alliance

Report topic: "Application of Chinese medicine with the same source of medicine and food as feed additives in a reduced resistance environment and the impact of the mother-child integrated health care program The role of sows and piglets"

Professor Li said that 117 kinds of Chinese medicines have been included in the "Catalogue of Feed Ingredients" under the reduced resistance environment, providing a platform and opportunity for the application of Chinese medicines in new green feed additives. It also explained the functions of plantain, eucommia leaf, hawthorn and other traditional Chinese medicines, and pointed out that they can all be used as feed additives.

is based on the environment of non-plague resuming production and reduced resistance, starting from postpartum lack of milk, blood loss symptoms , talking about the problems encountered by sows after delivery, Professor Li said that a mother-child integrated dosing program was established through compound Chinese veterinary medicine. It can alleviate the problems of dry stool, insufficient milk and low feed intake of reproductive sows. At the same time, it can improve the problems of low weaning litter weight, high diarrhea rate, and lack of high-quality breast milk.

Deficiency of qi and blood can cause postpartum lack of milk, no food, stillbirth, etc. Bazhen Decoction can nourish both qi and blood. Bazhen decoction prescriptions (astragalus, fried atractylodes, poria, roasted licorice, white peony root, rehmannia glutinosa, angelica, chuanxiong, etc.) except for rehmannia glutinosa, are all medicine and food feed additives. In terms of the pharmacological effects of Bazhen Decoction, it can improve the bowel condition; promote the immune status of red blood cells; supplement Qi and blood, increase the expression of peripheral blood red blood cells and EPO mRNA, promote the proliferation of T lymphocytes, and increase the hematopoietic area of ​​bone marrow; Sows with postpartum weakness, more lying and lack of milk, can return to normal milk production.

After experiments, it has been found that medicine and food homologous Chinese medicine as a feed additive and integrated health care for mother and child can improve the overall condition of reproductive sows and piglets and improve production performance.

Speaker: Dr. Wang Dezhong, Technical and Strategic Consultant of Guangdong Ruisheng Technology Group Co., Ltd.

Report topic: "No Anti-Education Trough"

Dr. Wang first talked about the reasons for the use and prohibition of antibiotics, taking the new crown pneumonia virus as an example to illustrate The rate of the autoimmune system overcoming the disease may reach 96%.

has successfully raised rabbits without resistance, and the results show that acidifier plant essential oil is a good combination of anti-anti-additives. Demonstration of the mechanism of action of essential oils and acidifiers, and the mechanism of organic acids on pH-sensitive microbial populations: First, only undissociated acids can enter microbial cells. Once in the cell body, the acid will dissociate quickly (the difference between pKa and pH) Causes its separation), pH decrease-consumes energy to maintain the pH balance in the body, the accumulation of toxic anions prevents DNA synthesis, disrupts protein synthesis, and finally cell death. In addition, experiments have shown that organic acids can control molds and bacteria, And introduced the essential oil product development process. Dr. Wang said: The future of compound essential oils should look like this-feed preservation, antibacterial, immune regulation, etc., with functions of epidemic prevention, quarantine, and biological safety.

Speaker: Dr. Wu Changzheng, Shanghai Yuanyao Agricultural Co., Ltd. Specially Invited Expert

Report topic: "Solution of raw materials in the context of no resistance"

African swine fever is rampant, the anti-resistance decree is strictly enforced, and our colleagues in the breeding industry are coming That is undoubtedly a huge challenge. It is true that anti-rescue has never been accomplished overnight, and a single factor affects events. It needs to be grasped from many aspects as a whole. The main ideas of anti-fighting are as follows: starting from five aspects of raw material quality, precise nutritional formula, functional additive combination, feed processing technology, and feeding management.

For weaned piglets, improving the intestinal health, reducing diarrhea and promoting their growth is the key. For weaning piglets to develop alternative anti-raw materials, choose high protein yeast culture, bacteriostatic soybean meal fermentation protein, Lactobacillus acidophilus culture (SSR), bacteriostatic soybean meal fermentation protein Lactobacillus acidophilus culture = double inhibition bacteria. promotes digestion and absorption; the body's immune level is improved; the intestinal mucosa function is sound; the intestinal microecological flora is balanced. To achieve the purpose of reducing diarrhea and promoting growth. In addition, it should be noted that yeast culture can effectively replace expensive protein materials, is safe, reliable, and cost-effective.

In addition, Dr. Wu introduced three high-quality raw materials produced by Shanghai Yuanyao. They are high-protein yeast culture (with delicious flavor): high-protein raw materials with high digestibility and unlimited addition; antibacterial soybean meal fermented protein (Bole-V): deep-fermented soybean meal that can inhibit bacteria and sterilize; acidophilic Lactobacillus culture (SSR): highly effective antibacterial, focusing on piglet intestinal health. The dual effect of antibacterial soybean meal fermented protein and Lactobacillus acidophilus culture can double antibacterial. Precise nutrition and strict quality control of raw materials are the guarantee for achieving "feed without resistance".

Speaker: Professor Wang Junjun, Associate Dean of the College of Animal Science and Technology, China Agricultural University

Report topic: "Characteristics of colonization of intestinal microbes in the neonatal period of weak piglets and their targeted intervention"

Professor Wang from the characteristics of colonization of intestinal microbes and their targeting The direction of intervention proposes a solution to the intestinal problems in the newborn period of weak piglets, which is divided into three parts: weak piglet newborn period intestinal microbial colonization characteristics and its influence on the intestinal microbial structure and digestion and metabolism in the later stage, and affect the newborn Factors for colonization of intestinal microbes in early piglets and targeted intervention of intestinal microbial colonization in weak piglets.

first mentioned the negative effects of weak piglets and their individual variation on pig production, such as: slaughter at the same time, increased management costs, restricted precise nutrition; poor adaptability and growth performance, poor immune function and meat quality, and high mortality in the newborn period Wait. It was found through experiments that the difference between normal and low-born pigs intestinal microbial colonization is mainly reflected in the 7-21 days of age. Experimental data such as phylum level, genus level and short-chain fatty acid production indicate the characteristics of intestinal microbial colonization in the neonatal period of weak piglets. Experiments have shown that IUGR weakens the intestinal development of growing pigs by changing intestinal microbial colonization and hindgut barrier function; IUGR growing pigs have low portal vein net absorption, reduced small intestinal absorption capacity, and increased large intestine fermentation capacity; the difference in cecal fermentation is mainly due to small intestinal digestion Absorption capacity and composition of ileal chyme.

The factors that affect the colonization of intestinal microbes in newborn piglets, mainly emphasize the impact of the intestine on piglets. Experiments have found that milk and fecal microbes can be transmitted vertically to affect the colonization of piglets’ mucosal microbes. IUGR pig organ development features: skeletal muscle and small intestine Developmental hindrance, reduced intestinal nutrient metabolism and oxidation balance protein expression in IUGR piglets, increased expression of stress protein, and insufficient supply of amino acids in the arginine family are important reasons for the formation of IUGR.

To reduce the occurrence of weak piglets, it is necessary to add Gln from the gestation period to reduce IUGR and piglet birth weight variation, improve piglet intestinal development, and carry out nutritional intervention for growing pigs from a microbiological perspective.

Speaker: Wu Bing, General Manager of Yangzhou Leading System Engineering Co., Ltd.

Report topic: "Enzymatic hydrolysis and fermentation of biological feed, equipment design and application"

report is divided intoThe development situation and significance of China's biological feed, main fermentation equipment, fermentation process plan, and introduction of Yangzhou Leading System Engineering Co., Ltd., fermented feed terminal customers and technical partners.

First, Mr. Wu introduced the development situation and significance of China's biological feed.

Development situation: Starting from July 1, 2020, feed manufacturers stop producing commercial feeds containing growth-promoting drug feed additives (except for Chinese herbal medicines). Biological feed has ushered in a broader space. Biological feed is the general term for safe, efficient, environmentally friendly, and residue-free high-quality feed and feed additive products developed through genetic engineering, protein engineering, fermentation engineering and biological extraction. Feed biological products account for 20% of feed value, but determine 80% of feed quality. Significance: to save food, slow down competition between humans and animals, reduce environmental pollution caused by the breeding industry, solve the problem of feed resources and the lack of feed additives, and ensure the quality and safety of animal products, thereby improving human public health and safety at the end of the food chain and bringing about economy Benefits and good social benefits.

Next, talking about the main fermentation equipment at present, including wet powder mixer, pellet differential pressure weighing mixer, wet material quantitative packaging system, tipping hopper feeder, stainless steel liquid heating tank, micro strain adding machine, fermentation The production line is fully automated control system , etc. Six kinds of fermentation process schemes were analyzed in detail, and the work flow and characteristics of the process were demonstrated with animation. A brief introduction to the company’s situation, Yangzhou Leading System Engineering Co., Ltd. was established in 2011. It has been involved in the fermentation material industry since 2014. From the early stand-alone equipment to the current complete turnkey project, it provides customers with one-stop integration, Customized service of fermentation production process and equipment.

Speaker: Dr. Liu Hongwei Superstar Agriculture and Animal Husbandry Co., Ltd.

Report topic: "Research and Application of Fermented Feed in Pigs"

analyzed the industry situation and technical demand analysis. In the context of African swine fever, we should think about how Let pig raising enter the post-non-epidemic era, the feed end will enter the era of no resistance, the value of live pigs will be reconstructed, and the industry chain will be extended; pig raising is in a period of huge profits; artificial intelligence, etc., have promoted the development of the pig industry and have Technology makes demands. Fermented feed needs to meet disease-resistant nutrition, nutritional parameter optimization, functional raw materials/additives, meat quality improvement technology, precise nutrition and feeding, and development of low-protein NE system with unconventional raw materials, and low-protein NE system biotechnology.

The current mainstream product of fermented feed is wet fermented feed , and the current research is mainly carried out in two aspects: single raw material fermentation and mixed raw material fermentation . In the single raw material fermentation, high-moisture fermented soybean meal has a better test effect on nursery pigs, while the test effect of fermented rapeseed meal on fattening pigs is not good, and further research is needed. The fermentation of mixed raw materials and high-moisture mixed concentrate fermentation has been remarkable in commercial pigs. The effect at each stage is large pigs> middle pigs> nursery pigs, which can reduce the level of diarrhea. Research on high-moisture mixed coarse feed fermentation on sows, the effect is unstable. In addition, special attention should be paid to the improper addition method that affects the product variation coefficient and summer feed mildew (mixing uniformity).

fermented feed is the general trend. The fermentation effect of roughage and unconventional raw materials needs to be further studied, and the fermentation effect of concentrate and single soybean meal is the best. The integrated and collaborative research of fermented feed in microbiology, biochemistry, animal nutrition and feed processing and modulation needs to be strengthened, and there are still many blind spots.

Speaker: Xianghongxing Microbial Fermentation Expert and Microbial Engineer

Report topic: "New Microbial Fermentation Technology and Feed Processing"

Mr. Xiang first introduced the industry background of biotechnology applications, and comprehensively analyzed biotechnology applications from the national and industry levels The importance of. Then talk about the current biotechnology application examples and the nature and bottlenecks of feed production and processing, the essence of which is: combinatorial skills---nutrition formula combination---purchasing quality control; the bottleneck encountered is: the lack of deep transformation capabilities for raw materials. The origin of the application of

biotechnology in the feed industry is water, and water activity and temperature are the prerequisite and key to the revolution in feed technology.

A new revolution in feed processing technology---biological feedthe road.

feed is completely forbidden, nutrition and antibacterial. It is necessary to increase the added value of fermented products-antibacterial replacement. The first step is to screen strains. Initial: large amount of bacteria, fast and coarse screening; re-screening: specific and precise screening, repeated many times. Secondly, the performance of the bacteria was identified. Experiments showed that through the combination of special bacteria liquid and solid fermentation bacteria, fermented soybean meal can produce good antibacterial effects. The breeding of

also needs to be linked to equipment. Mr. Xiang mentioned energy-saving dryers and wet material quantitative systems, environmentally friendly closed-loop technology-comprehensive utilization of exhaust gas, closed-loop heat pump fermentation and drying integrated machine (aerobic fermentation), fermentation barrel (automatically controlled Temperature, one-way exhaust, multi-energy, remote data transmission).

The transformative nature of future feed technology and equipment: from traditional feed processing to physical blending. Welcome the arrival of complete biological feed, including anti-nutritional factor removal, in vitro pre-digestion of nutrient components, nutrient release, detoxification, transformation of microbial metabolites, active microorganisms and micronutrition, antibacterial, mycotoxin decomposition, in vitro chemical balance, etc. , Combine the innovation of different feeding modes. At the end of the

conference, the organizers set up a special salon discussion session. Specially invited expert Dr. Wu Changzheng from Shanghai Yuanyao Agriculture Co., Ltd. guest-hosted the forum, Professor Wang Junjun, deputy dean of the College of Animal Science and Technology of China Agricultural University, and Juxing Agriculture and Animal Husbandry Co., Ltd. Pig Dr. Liu Hongwei, Director of Nutrition, Dr. Wensen Zhu from Beijing Enruikang Agricultural Technology Consulting Co., Ltd., Dr. Jin Wei, Vice President and Technical Director of Zhengtai Group, Dr. Wu Bing, General Manager of Yangzhou Leading System Engineering Co., Ltd., Microbial Fermentation Expert and Microbial Engineer Xiang Hongxing The guests of the forum conducted in-depth discussions with the theme of "New Biotechnology and Piglet Nutrition Application", mainly discussing "the significance and application of biological feed in the current industry background, the main problems and solutions that tend to occur in the application process", "no The problems and solutions faced by piglets under anti-environment, "the feasibility of bio-fermentation complete feed, the future trend and core of fermentation equipment manufacturing", and "research on intestinal microbiome and piglet health", etc. During the Q&A session, there were also enthusiastic interactions on and off the stage.

Sharing of new biotechnology and piglet nutrition application

This forum is a feast for the academic world, the collision of ideas, the in-depth exchange of ideas, the front-end knowledge of the forum is full of front-end discussions... Knowledge returned to their respective jobs and continued to contribute to the development of animal husbandry. I believe that through the concerted efforts of colleagues in the animal husbandry industry, a new chapter will be written for China's feed industry!