Hong Kong director Chen Musheng passed away on the morning of August 23 at the age of 58. He was nominated for Best Director five times during his lifetime. His representative works include "New Police Story", "Baby Project", and "Anti-drugs". He felt unwell during the directing of "Rage: Serious Incident" starring Donnie Yen and Nicholas Tse. After that, he went for a physical examination and found nasopharyngeal carcinoma advanced stage.
Chen Musheng
According to the World Health Organization, about 80% of nasopharyngeal cancers occur in Asia, and China accounts for 50% of the total. The age of onset of nasopharyngeal carcinoma has two peak periods, the first peak is 15 to 25 years old, and the second peak is 50 to 59 years old. In recent years, the incidence of nasopharyngeal carcinoma has shown a younger trend.
Symptoms: Be alert to the 7 big signals
Nasopharyngeal carcinoma is common in the seven danger signs. If the following symptoms persist for more than 2 weeks, they should be checked as soon as possible.
headache: nasopharyngeal lesions invade the skull base bones, nerves, blood vessels, etc., which will cause persistent unilateral headaches, including the frontal, temporal, top and occipital areas. If the condition progresses to an advanced stage, persistent headaches can easily be mistaken for neuralgia.
tinnitus, ear stuffiness , hearing loss: lesions occur in the side wall of the nasopharynx or the mouth of the Eustachian tube, the tumor compresses the Eustachian tube and causes unilateral tinnitus or hearing loss, catarrhal otitis media , etc.
nasal mucus with blood streaks: most patients withdraw bloody nasal mucus from the nasal cavity and spit it out from the oropharynx. This kind of "pharyngeal" nose bleeding has a higher chance of missed diagnosis and misdiagnosis.
nasal congestion: has mechanical nasal congestion due to the obstruction of the nostril after the tumor. The enlargement of the advanced tumor can cause nasal congestion on both sides.
cervical lymph node swelling : is mainly the swelling of the lymph nodes in the upper deep layer of the sternocleidomastoid muscle, the swelling is solid without tenderness, and it is not easy to be pushed. As the tumor develops, it can compress the glossopharyngeal nerve, vagus nerve, accessory nerve, and hypoglossal nerve, which manifests as soft palate failure, difficulty swallowing, vocal cord paralysis, and one side of the tongue shrinks and shifts to the affected side.
cranial nerve symptoms: tumor spreads into the skull through the rupture hole, facial numbness, diplopia, blurred vision, eyelid drooping , strabismus may occur. Metastatic lymph nodes in the deep neck can compress the nerves at the base of the skull, resulting in hypoesthesia in the throat and paralysis of the soft palate.
tumor metastasis: nasopharyngeal carcinoma metastasis can invade the eyes, brain, bone, lung, liver and other tissues, especially the lung, liver and bone. If the body has fixed stubborn pain in certain bones, frequent bloody sputum with chest pain, hepatomegaly, severe vision loss, etc., you should be alert to cancer metastasis.
Prevention: Nasopharyngeal cancer is related to four major factors
Nasopharyngeal cancer may be related to Epstein-Barr virus infection, environment, diet, genetic susceptibility factors, etc. Therefore, you should avoid exposure to chemical carcinogens in your life, and do not eat pickled, spicy, fried Avoid long-term inhalation of dry, dusty and irritating gases, such as irritating food, and do not smoke and inhale less toxic fumes. At the same time, regular drips of nourishing and moisturizing preparations can be used to avoid the use of drugs or preparations that strongly constrict blood vessels.
treatment: radiotherapy is the first choice for the treatment of nasopharyngeal carcinoma
. Radiotherapy is the first choice in the treatment of nasopharyngeal carcinoma. Firstly, because nasopharyngeal carcinoma is mostly poorly differentiated squamous cell carcinoma , it is more sensitive to radiotherapy; secondly, the nasopharyngeal area is special, located in the center of the face, and the peripheral neurovascular structure is complicated. These vascular and nerve tissues can tolerate radiotherapy well and are not prone to severe damage; third, nasopharyngeal carcinoma is particularly prone to lymph node metastasis and lymph node metastasis in the neck. About 70% to 80% of patients are in At the time of treatment, there were cervical lymph node metastases, and surgery is difficult to achieve effective treatment for these patients.
The use of modern radiotherapy methods such as intensity-modulated radiotherapy and image-guided radiotherapy has increased the 5-year cure rate of nasopharyngeal carcinoma from 30% in the 1950s to more than 80% now, and the 5-year control rate of early cases Up to 90%.
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