Re-publish the top issue, a "Science" from Fudan University, and a "Cell" from Shanghai University of Science and Technology

Generally speaking, there are three well-known top journals in the scientific community, namely Science, Nature and Cell, which are generally referred to as CNS.

On January 30, the internationally renowned journal "Science" (Science) published an online publication affiliated with Fudan University The research paper "Structure of Nucleosome-bound human BAF Complex" (the structure of human-derived BAF complex bound human nucleosome) by Xu Yanhui's research group from the Cancer Hospital and the Institute of Biomedical Research. This result reported that the human-derived chromatin remodeling complex BAF combined with the cryo-EM structure of nucleosomes played an important role in understanding the mechanism of chromatin remodeling and the carcinogenic mechanism of BAF high frequency mutations.

The Cancer Hospital of Fudan University and the Institute of Biomedical Sciences are the joint first units. Fudan University postdoctoral fellow He Shuang, 2016 doctoral student Wu Zihan, 2014 doctoral student Tian Yuan are the co-first authors of this article, and Xu Yanhui is the corresponding author. The Imaging Center of the Institute of Biophysics of the Chinese Academy of Sciences, the Electron Microscopy Center of Shanghai University of Science and Technology, the National Protein Center, and the Electron Microscopy Center of Fudan University under construction have given important support to data collection.

On January 31, the research team of Liu Zhijie, executive director of the iHuman Institute of ShanghaiTech University and professor of the School of Life Sciences and Technology, published a research paper "Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex" in the internationally renowned journal "Cell". Structures",

It is reported that this is the third major research result of the Shanghai University of Science and Technology Liu Zhijie's research group following the continuous publication of research papers in Cell in 2018 (February 2) and 2019 (January 10). Associate researcher Hua Tian of Shanghai University of Science and Technology, Li Xiaoting, postdoctoral fellow, and Associate Researcher Wu Lijie of the iHuman Research Institute membrane protein line platform are the co-first authors of the paper, Professor Liu Zhijie and Associate Researcher Hua Tian are the co-corresponding authors, and Shanghai University of Science and Technology is the first completion unit.