Japanese study: Omicron BA.5 from onset to moderate, 6 adults worsened within 3 days after onset

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Japanese study: Omicron BA.5 from onset to moderate, 6 adults worsened within 3 days after onset - Lujuba

Since Covid-19 has swept through for nearly 3 years, human beings have seen powerful virus strains continue to mutate during this period, and one after another variants have appeared, from Alpha, Delta, Beta, etc., to today's Omicron BA.5, All countries dare not take it lightly.

Studies have pointed out that the Covid virus evolves, circulates, reproduces and mutates over time, resulting in the emergence of more and more different mutant strains. Whenever a dominant variant appears in a period, it will kill the previous virus in a short time, which is why we don't see more than two variants dominating the same period and at the same time. After the fourth wave of the

epidemic starting in April 2021, specific mutant strains have become mainstream.

In Japan, the 4th wave is Alpha, the 5th wave is Delta, the 6th wave is Omicron BA.1, and now the 7th wave Omicron BA.5 has become mainstream, and the infection wave is the largest ever.

Japanese study: Omicron BA.5 from onset to moderate, 6 adults worsened within 3 days after onset - Lujuba

Omicron BA.5 is a mutant strain of the Omicron branch that emerged in November 2021, and has the characteristics of being highly infectious and capable of infecting people who have been vaccinated and who have been infected with COVID-19 in the past.

Then, what kind of symptoms will appear in people infected with this BA.5, and to what extent will they be aggravated?

July 28th, Fukui newly infected more than 1,000 people with COVID-19, and the "7th wave" of the epidemic is spreading:

BA. Judging from the symptoms of BA•5-positive patients, over 70% of them have fever, and 50% each have sore throat and cough. According to the county, "the fever lasted for about 2 days, and the body temperature suddenly rose and fell," and the symptoms recovered within 5 days.

July 18-24, the county's investigation of new infection routes showed that 70.9% of people confirmed "BA·5".

After June 27, after surveying the symptoms of 118 patients who were positive from BA·5 , 74.6% of them had a "fever above 37.5 degrees", most of which were 39 degrees; followed by "sore throat" 51.7% and "cough" 50.8%. 11.0% of the symptoms that have not been seen so far are "nausea and vomiting", which are said to mostly appear in young children.

Clinical symptoms of 39,956 BA.5 infected persons in Sapporo during the epidemic period

Japanese study: Omicron BA.5 from onset to moderate, 6 adults worsened within 3 days after onset - Lujuba

The longest duration of symptoms was "sore throat", lasting an average of 4.2 days. Miyashita Hirofumi, deputy director of the County Health and Welfare Department, explained: "The pain lasted until about the third day, and then the pain gradually disappeared. To prevent high fever at night, etc., prepare antipyretics and oral rehydration fluids at home, and encourage people to drink water frequently , to prevent dehydration.

Japanese study: Omicron BA.5 from onset to moderate, 6 adults worsened within 3 days after onset - Lujuba

In addition, , The frequency of fever above 38 degrees varies significantly according to age. About 60% of people under 10 years old have fever, while only about 15% of people over 70 years old have fever.

z Generally speaking, the older you are, the more difficult it is to have a fever when you are infected. Although the elderly do not have a fever, it cannot be said that it is definitely not a new crown infection!! convulsions increased, although the frequency of severe cases is very low, but it is necessary to carefully observe the situation.

Frequency of severe cases at each age

Japanese study: Omicron BA.5 from onset to moderate, 6 adults worsened within 3 days after onset - Lujuba

Severity of Covid-19 infections in Hiroshima Prefecture from the 3rd wave to the 7th wave (from the Hiroshima Prefecture Health and Welfare Bureau data)

The data shows that the severity of the infection exceeds Moderate II (need to give Oxygen) infection, the incidence rate of the fourth wave dominated by the Delta strain was the highest at 9.3%, and the seventh wave was 0.6%, which was the lowest in history, among which the elderly who were most prone to exacerbations aged 60 and above also dropped to 3.5%.

In addition, judging from the number of vaccinations, among the patients aged 60 and over who were infected in July, 8.3% were not vaccinated, while only 2.3% were vaccinated three times, indicating that vaccine can prevent BA.5 The effect is still in effect.

In addition, there is a report from Denmark that from the perspective of hospitalization rate, BA.5 is 1.65 times that of BA.2, indicating that the pathogenicity of BA.5 itself may be higher than that of traditional Omicron strains. As the elderly and people with underlying diseases have completed the third and fourth vaccinations, the severity may have decreased by the sixth wave.

Severity time

Japanese study: Omicron BA.5 from onset to moderate, 6 adults worsened within 3 days after onset - Lujuba

Distribution of days before the exacerbation of covid-19 infection in Hiroshima Prefecture (from Hiroshima Prefecture Health and Welfare Bureau data)

In traditional new coronavirus infection, some people became seriously ill within about a week after onset. Although Omicron is less severe, symptoms are known to worsen faster than the new variant!

According to the data from the Hiroshima Prefecture Health and Welfare Bureau mentioned above, the time from onset to moderate II (requiring oxygen) deterioration in the 7th wave of infected persons with BA.5 as the mainstream is shorter than that of the traditional Omicron strain, and 60% of them Aggravated within 3 days of onset!

This also explains from the side why some elderly people walk in a hurry after getting sick. It is really not careless at all! ! !

thus also shows that early diagnosis and early treatment are more important than ever, because in covid-19 infection, by starting treatment early, serious illness can be prevented.

In addition, more and more people are getting serious with disease exacerbations and bacterial infections like aspiration pneumonia , but not necessarily exacerbations caused by covid infection itself, but exacerbations due to underlying conditions, which This requires healthcare organizations to assess and respond appropriately more carefully than ever before.

Infection control is important

To be precise, "whoever is infected, the situation is not good", but if unfortunately infected, home care is necessary, otherwise it may become more serious:

・Wear a mask indoors, eating time Also try to shorten the time to remove the mask as much as possible

・Avoid crowds

・Wash your hands frequently

It is still very important to continue to take basic infection control measures. At the same time, three times of vaccination can improve the infection prevention and severe prevention effects of the new coronavirus.

In Omicron, the infection prevention effect of the vaccine is decreasing, even if it is vaccinated 3 times, it is possible to be infected, but the amount of virus shed by the person who has been vaccinated 3 times will also be reduced when infected, so it is difficult for people around to be infected.

In addition, the elderly and people with underlying diseases can prevent further aggravation of the disease through the fourth vaccination.

コロナ「BA·5」のsymptoms, cure dayNumber を investigation

new type of カロナオミクロン strain BA.5によるsymptoms の特徴について serious illness するfrequency やそのperiod?

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