You may have heard that every 2 hours in China, 6 women die from cervical cancer.
There are still 130,000 women suffering from cervical cancer each year. Unlike the plummeting incidence of cervical cancer in European and American countries, cervical cancer has become one of the fastest growing tumors in China in the past ten years. What is even more frightening is that cervical cancer is gradually "favoring" young women. "I have seen the youngest person with cervical cancer at 22 years old, which I could not imagine more than a decade ago." Sun Yat-sen University Cancer Center Said , deputy chief physician of gynecology Huang He.
But what you don’t know is that cervical cancer is hailed as the first human tumor that can be prevented and eliminated. This is because scientists have found the “culprit” that causes cervical cancer-human papillomavirus (HPV) Therefore, early vaccination of cervical cancer vaccine with means that it will greatly reduce or even prevent the occurrence of cervical cancer for life.
Recently, the launch of 's first domestically-made bivalent cervical cancer vaccine, , has aroused the attention of many citizens. In the past, HPV vaccines were only approved for production in the United Kingdom and the United States, while imported vaccines were basically "limited supply" and were launched 2 years ago. Nine-valent cervical cancer vaccine is still in short supply everywhere. Experts predict that the domestic HPV vaccine will effectively alleviate the shortage of vaccines after it goes on the market, and the price will also have an impact on imported vaccines.
It is unimaginable that HPV vaccine still has a 1 billion gap in China.
In 2017, the cervical cancer bivalent vaccine and the tetravalent vaccine were successively launched in my country. One year later, the cervical cancer nine-valent vaccine also obtained shelf registration approval, but it was imported. The amount of vaccine issued is controlled. According to data from the China Institute for Food and Drug Control, from January to November 2019, the number of HPV vaccines issued was 8.7 million, the number of bivalent HPV vaccines was 1.7 million, the quadruple price was 4.4 million, and the nine price was 2.6 million. Compared with two years ago, the amount of
issued has increased by six times. However, from the feedback from various regions, the HPV vaccine is still in short supply, especially the 9-valent vaccine. The relevant personnel of the county and district health institutions said that they are basically out of stock. Status, I don’t know when it will be available. If we calculate the 356 million women of the right age in my country, each with 3 needles, the market gap will exceed 1 billion.
Although the nine-valent vaccine is the most popular, there is also a market for bivalent and quadrivalent vaccines in China, mainly because China has strict control over the age groups suitable for the three HPV vaccines, " bivalent HPV vaccine suitable age groups The tetravalent vaccine is 9-45 years old, the quadrivalent is 20-45 years old, and the nine-valent vaccine is approved for women aged 16 to 26. "" Huang He said that the price difference between different vaccines will also cause different choices for women. The bivalent HPV vaccine is 600 yuan per shot, the quadrivalent HPV vaccine is 800 yuan per shot, the nine-valent HPV vaccine is as high as 1,300 yuan per shot, and the domestic bivalent HPV vaccine is reduced to 329 yuan per shot. The cost of a total of three shots is much lower. , Reducing the burden on women.
What is the difference between the different "prices" of cervical cancer?
In addition to the well-known price differences, what are the differences between different "prices"? Huang He said that in fact, the "price" mainly represents the type of virus that the vaccine can prevent.
Scientists have discovered that there are two main types of HPV viruses that cause cervical cancer, one is HPV16 and the other is HPV18. The bivalent HPV vaccine is aimed at preventing these two viruses and can prevent 84.5% of cervical cancers.
With the discovery of medical research, HPV virus can not only cause the occurrence of cervical cancer, but also the murderer of condyloma acuminatum. Therefore, HPV6 and HPV11 are added on the basis of HPV16 and HPV18, and become a quadrivalent vaccine.
just said that the bivalent vaccine can only prevent 84.5% of cervical cancers. In order to make the prevention rate close to 100%, scientists have discovered that HPV 31, 33, 45, 52, and 58, these five high-risk HPV subtypes can also After cervical cancer is increased, the prevention rate of cervical cancer is increased to more than 90%.
have sex, do you still need cervical cancer vaccine? As a preventive vaccine, the best time for vaccination is before the woman has had sex. Therefore, the World Health Organization recommends that 9-14-year-old adolescent women benefit the most from HPV vaccination, and the antibody level is other More than 2 times the age.
If women who have had a history of sex, or even a childbirth history, still need to be vaccinated against HPV, it is currently controversial, but it is undeniable that they can still benefit.
Yellow Crane pointed out that there are relatively few cases of simultaneous infection of two or more high-risk HPV viruses. Therefore, the vaccine can always cover part of the HPV virus. In addition, HPV vaccination can prevent the virus from reinfecting or reduce the recurrence rate of the disease. This is mainly a cost-effective issue."
After being vaccinated with cervical cancer vaccine, it does not mean everything is worry-free.
We can say that cervical cancer is 100% related to HPV infection, but at present, more than 200 HPV viruses can be identified by medical methods. There are no less than a dozen types of cervical cancer related. Even the nine-valent cervical cancer vaccine cannot fully cover the high-risk HPV virus. In addition, all vaccines have an expiration date.
Therefore, after being vaccinated for cervical cancer, it cannot be said that cervical cancer will not occur 100% in the future. "However, in addition to vaccination, we can do regular cervical cancer screening every year , early detection, cervical cancer cured The rate is as high as 90% or more." Huang He reminded. Breeze Plan Health Science Qualifying 39 Health Super Team